Intracytoplasmic Sperm Injection has been applied across the world in order to increase the chances for fertilization and to alleviate problems related to severe male infertility. It is a source of great hope for couples that have tried all other fertility treatments. ICSI gives them & chance to fulfill their dream of parenthood.
ICSI is a form of micromanipulation that involves the injection of single sperm directly into the cytoplasm of the mature egg (oocyte). The process increases the chances of fertilization to take place in case the fertilization would have failed due to the presence of abnormalities in sperm. It helps to choose the high quality sperm, which are motile, morphological, & best for the process of fertilization.
The procedure includes the retrieval of mature eggs from the female partner during standard IVF cycle. The male partner’s semen sample is prepared in the lab in order to obtain the most motile and healthy sperm. The retrieved eggs are allowed to rest for 4-6 hour in order to determine that whether they are matured enough to undergo ICSI.
These matured eggs are then held through a special holding needle of the micromanipulator and then with the injection needle is used to pick the most motile and healthy sperm with great precision. The sperm is then inserted into the egg. The injected eggs are placed into an incubator overnight and are then checked the next morning to see if fertilization has taken place or not.
In what conditions ICSI is required:
- If the numbers of sperm are low and are immotile.
- Severe teratospermis (abnormal sperm)
- Presence of antibodies in sperm
- Prior or repeated fertilization failure with standard IVF
- Frozen sperms are low in number and quality
- Obstruction of the male reproductive tract that can’t be repaired. Sperm may be obtained from the epididymis by a procedure called microsurgical epididymis sperm aspiration (MESA) or from the testes by testicular sperm aspiration (TESA).
ICSI helps to reduce the chances of multiple pregnancies and a couple undergoing ICSI has better chances of conceiving as compared to one who is undergoing a standard IVF cycle. In case if only very few sperms are available then ICSI is the most recommended treatment for an infertile couple which can help them to experience the journey of parenthood.
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